Alyssa Jayne Milano was born on December 19, 1972 in Brooklyn, New York, and is the daughter of a musical director and a fashion designer. She grew up with Staten Island with her brother and was educated in Pacific Hills School after being home schooled.
At a very young age she had acting stints including that of television commercials and off-Broadway productions.
Her first major television role was on Who's the Boss?. She made more adult appearances on her later films like Casualties of Love: The Long Island Lolita Story, Embrace of the Vampire, Confessions of Sorority Girls, Deadly Sins, and Poison Ivy II: Lily. Her major television appearances were on Melrose Place, Spin City and Charmed. She was married to Cinjun Tate however they divorced eleven months after their marriage in 1999.
Exceptional Performance by a Young Actress Starring in a Feature Film - Comedy or Drama for: Commando (1985).
Appeared in Blink 182's music video "Josie" as Josie.
Outstanding Individual Achievement for Voice Acting by a Female Performer in an Animated Feature Production
for: Lady and the Tramp II: Scamp's Adventure (2001)
Best Young Female Superstar in Television for: "Who's the Boss?" (1984).
Best Young Actress in a Special, Pilot, Movie of the Week or Mini-Series
for: Dance 'Til Dawn (1988) (TV).
Exceptional Performance by a Young Actress, Starring in a Television, Comedy or Drama Series
for: "Who's the Boss?" (1984).